Our Research

In response to growth factors and nutrients, target of rapamycin (TOR) plays essential roles in a wide array of cellular processes including protein translation, gene transcription, apoptosis and autophagy. Dysregulation of the mammalian TOR (mTOR) signaling pathway is involved in the development of diseases including cancer and metabolic disorders.

Using biochemical and genetic approaches, we investigate the function and regulation of the mTOR signaling pathway and the role of mTOR signaling in disease.