June 30, 2021

Researchers have demonstrated that a natural compound produced by lichens can block the activity of a protein that is central to the gene-activation process. The research, conducted in human-derived breast cancer cells, points to this protein as potential therapeutic target.

Anna Mapp, Ph.D.
December 18, 2020

Researchers are advancing a novel approach to developing antivirals against SARS-CoV-2, with support from the LSI’s Klatskin-Sutker Discovery Fund

Image credit: PNAS; (CC BY-NC-ND 4.0)
October 30, 2020

New research is challenging a long-held understanding of how two types of cellular proteins cooperate to activate genes. The findings improve the possibility of targeting these interactions with small-molecule drugs.

Brittany Morgan, Ph.D.
April 24, 2020

In the Michigan Life Sciences Fellows program, May-Walt Fellow Brittany Morgan, Ph.D., has found a balance of independence and community that will serve her well as she prepares for her independent scientific career. Learn how this 'super postdoc' program is helping fellows get a step ahead in their early careers and developing the next generation of scientific leaders.

January 24, 2019

Four teams of graduate students and postdoctoral fellows will soon launch their own cross-lab, interdisciplinary projects, with funding from the LSI Cubed program.

August 20, 2018

Researchers have determined how to target a class of proteins that have long been considered too “fuzzy” to target with small molecules, opening the door to new drug-discovery projects.

January 31, 2018

Findings remove a barrier to developing potential therapies for cancer patients with poor prognoses.

Mitchell Meyer
September 25, 2017

In the last century, Michigan was a driving engine of America’s manufacturing economy. Today, programs like the Perrigo Undergraduate Fellowship at the LSI are helping to fuel a new knowledge-based economy in the state.

December 8, 2016

How fly fishing can help explain a new frontier of drug discovery

Anna Mapp
November 1, 2016

Researchers blocked the dysregulated signaling associated with a 'master transcription factor,' which controls many different cellular decisions, without compromising its other biologically important functions.

February 12, 2015

Anna Mapp, Ph.D. has been awarded the 2015 Emil Thomas Kaiser Award from the Protein Society. The award recognizes a recent, highly significant contribution in applying chemistry to the study of proteins.