November 8, 2017

A previously dismissed genetic mechanism may contribute to nicotine dependence.

Colorful liver cells
November 6, 2017

Scientists identify a key driver of the progression to the most harmful form of fatty liver disease.

October 24, 2017

Reserach led by LSI affiliate faculty member Russell Ryan  provides new insights into how Notch drives the growth of B-cell cancers

Two molecules of restriction factor APOBEC3H form a sequence-independent complex with an RNA duplex.
October 18, 2017

Findings provide clues about how one protein utilizes RNA binding to get into the HIV cell and mutate the virus' DNA.

Daniel Klionsky
October 9, 2017

LSI faculty member Daniel J. Klionsky was recognized for consistently demonstrating outstanding achievements in research, teaching and mentoring, service and a variety of other activities. 

cryo-EM evolution (Credit: Veronica Falconieri, Sriram Subramaniam, National Cancer Institute, National Institutes of Health CC BY-NC 2.0)
October 5, 2017

LSI faculty members Michael Cianfrocco and Melanie Ohi explain the technology that won the 2017 Nobel Prize for Chemistry.

Stephanie Gates and Adam Yokom
September 25, 2017

How two U-M graduate students came to co-first author a high-impact paper and develop expertise in one of the hottest areas of biology.

Mitchell Meyer
September 25, 2017

In the last century, Michigan was a driving engine of America’s manufacturing economy. Today, programs like the Perrigo Undergraduate Fellowship at the LSI are helping to fuel a new knowledge-based economy in the state.

LSI building
September 18, 2017

The LSI expands its scientific reach with the addition of an affiliate faculty role. Affiliate faculty members will have labs located at the LSI — where they will have an adjunct appointment in addition to a tenure-track appointment in another unit on campus.

Melanie Ohi
September 14, 2017

The  welcomes structural biologist Melanie Ohi, Ph.D., to its faculty.

September 14, 2017

Researchers have discovered how an unlikely protein promotes cell division, even when the cell is treated with drugs to halt the process

Scientist examines image on a computer screen
September 6, 2017

To help attract early-career researchers of exceptional promise, the University of Michigan is launching a new, multidisciplinary, postdoctoral research fellowship program: the Michigan Life Sciences Fellows.

August 22, 2017

A mutation underlying the most common genetic cause of early-onset obesity was  thought to potentially protect patients from heart disease. New research shows otherwise.

August 17, 2017

This year’s annual symposium explores the galloping pace of discovery, bringing to campus five pioneers and innovators in different areas of bioscience technology and research. 

fruit fly germ cells
August 15, 2017

Connectivity between reproductive cells — or germ cells — in males serves as a quality assurance mechanism by making clusters of cells more sensitive to damage.

colorful fat cells
August 7, 2017

How a network of proteins and long noncoding RNA work together to push fat cells into fat-burning mode

July 18, 2017

International research team reveals why some species of cetaceans evolved sleek, muscular bodies while others grow to massive sizes

July 13, 2017

Research sheds new light on long-lasting changes that painful stimuli can exert at the level of a neural circuit — changes that can have a powerful impact on behavior.

July 5, 2017

After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a clinical trial.

schematic overview of new findings about LARP1's role as a molecular switch for mTORC1-mediated translation (Creative Commons, eLIFE)
June 27, 2017

A long-term collaboration reveals the critical role played by the RNA binding protein LARP1 for mTORC1-mediated translation of an important class of mRNAs, including those that encode ribosome proteins.

Tang commercial screenshot
June 22, 2017

After a file cleanup unearthed a 1970s Tang commercial staring LSI Professor Emerita Rowena Matthews, we reached out to her for the backstory.

June 21, 2017

How a new type of rapid-response defense mechanism  helps protect cells from environmental stress while giving slower, well-known protection systems time to act

June 16, 2017

New cryo-EM research reveals 3-D snapshots of how a key biological machine unfolds a ribbon of protein through its central channel.

May 24, 2017

Researchers have captured the first cryo-electron microscopy snapshots of a cellular target for Type 2 diabetes in action.

Roger Cone
May 18, 2017

LSI Director Roger Cone named to an additional role as the university's first vice provost and director of the biosciences initiative.