Artistic representation of LabGym's pattern images (left) feeding into an AI system to make a decision (represented by coding language and a bright spot on the right-hand side)
February 24, 2023

A team from tLSI has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors. The open-source software capitalizes on artificial intelligence to identify, categorize and count defined behaviors across various animal model systems.

Illustration of an abstract signaling tower, representing the carotid body, sending signals through the ganglion neurons (shown with fluorescent imaging).
February 6, 2023

New research from the lab of Peng Li, Ph.D., has uncovered the neural circuit in mice that activates sighing in response to low oxygen levels.

Connie Wu, Ph.D.
January 12, 2023

The LSI's newest faculty member, biomedical engineer Connie Wu, Ph.D., will explore new technologies to improve both diagnostic and drug-delivery tools, with clinical and basic research applications. Wu represents the LSI's first joint recruitment with the College of Engineering.

Illustrated interpretation of shield-1 binding to the CAPs pocket, thus releasing the bound peptide and activating its function.
December 8, 2022

A collaboration between two LSI labs has resulted in a new research tool for manipulating when and where cellular functions are activated, using the power of peptides.

October 13, 2022

A team of researchers from the University of Michigan and University of Utah has developed a new method for optimizing the tools that nature uses to build chemical compounds.

October 10, 2022

A new podcast and video series hosted by three faculty members from the University of Michigan, Cornell University and Columbia University explores what the future of cryo-EM will look like, while highlighting the career development and experiences of a wide range of experts in the field

Chelsey Spriggs, Ph.D., and Jay Brito Querido, Ph.D.
October 4, 2022

This fall, for the first time, the LSI is expanding its reach beyond the walls of Mary Sue Coleman Hall with the addition of two new faculty members. Learn how Chelsey Spriggs, Ph.D., and Jay Brito Querido, Ph.D., will advance the LSI's campuswide impact.

Jay Querido
October 4, 2022

Five questions with Assistant Professor Jay Brito Querido

Chelsey Spriggs, Ph.D.
October 4, 2022

Five questions with Assistant Professor Chelsey Spriggs

Voices of the LSI
October 4, 2022

"Voices of the LSI" is a quarterly column on the LSI’s work to cultivate a diverse, equitable and inclusive climate. This quarter, Adam Iliff, Ph.D., discusses how his own path to science shaped his involvement with the Aspirnaut Program, which helps connect high school students from under-resourced areas to their futures in STEM.

Janet Smith presents at the ceremony appointing her as the Rita Willis Professor of the Life Sciences
September 29, 2022

Janet Smith has been named the Rita Willis Professor of the Life Sciences, representing the first appointment to an endowed professorship at the LSI.

Normal liver tissue and a liver cancer nodule containing many dividing cells.
August 15, 2022

A hormone secreted by fat cells can restrain the growth of liver tumors in mice, according to a new study from the LSI. The findings offer a proof-of-concept for developing therapies against the most common form of liver cancer.

July 26, 2022

Researchers have developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally. The findings could lead to more efficient production of antibiotics that are effective against drug-resistant bacteria.

Voices of the LSI
June 28, 2022

"Voices of the LSI" is a quarterly column on the LSI’s work to cultivate a diverse, equitable and inclusive climate. This quarter, staff member Natalie Bartolacci, one of the institute's two DEI leads, reflects on what the LSI accomplished during its five-year "DEI 1.0" strategic effort and what lessons we can take into the next phase of our work to advance diversity, equity and inclusion.

Wenjing Wang and Kayla Kroning view cell imaging from a confocal micrscop
June 28, 2022

LSI Assistant Professor Wenjing Wang discusses the critical importance of supporting graduate students in the lab, and how philanthropic programs at the LSI are helping her students, and her entire research program, to thrive.

Melanie Ohi, Ph.D.
June 16, 2022

Researchers are pursuing a new potential culprit underlying Huntington’s disease, with an award from the Klatskin-Sutker Discovery Fund.

May 31, 2022

Scientists have identified a new role for a protein complex at the center of a human genetic disorder called Bardet-Biedl syndrome.

Voices of the LSI
March 15, 2022

"Voices of the LSI" is a quarterly column on the LSI’s work to cultivate a diverse, equitable and inclusive climate. This quarter, LSI Professor Bing Ye, Ph.D., considers scientific leaders' role in societal change and describes how trainees in his lab have helped expand his education and actions to advance diversity, equity and inclusion.

Artistic representation of biaryl bond formation through biocatalytic cross-coupling
March 2, 2022

Researchers have developed an efficient, greener strategy for constructing a common building block of many indispensable medicines and materials, using tools found in nature and sharpened in yeast.

 Wild type HeLa cells immunostained with antibodies against COMMD1 and VPS35
January 24, 2022

An obscure enzyme that normally operates deep within cells is also playing an unexpected role close to the cell surface—and is even required for cell migration—according to new research from the Life Sciences Institute.

Adipocytes (fat cells)
January 17, 2022

A new study led by the LSI demonstrates that blocking the activity of an enzyme inside fat cells can decrease obesity and related health disorders in mice.

Immunostaining of larval brains with and without overexpression of the protein Zelda
December 9, 2021

A team of scientists has identified a key player that drives both embryonic and neuronal stem cell fate, and demonstrated that this process must be precisely regulated to establish the developmental program in both embryo and neuronal tissues.

Voices of the LSI
December 1, 2021

"Voices of the LSI" is a quarterly column on the LSI’s work to cultivate a diverse, equitable and inclusive climate. In this column, Stephen Joy, Ph.D., reflects on his recent journey to share — and learn more about — his Japanese American family history and the challenges they faced during and after World War II.

A kinsesin bound to KIFBP
November 19, 2021

A new study has uncovered unexpected details about a key regulator kinesins, the molecular 'delivery trucks' that are essential for maintaining a healthy cellular supply chain.